Ruprecht-Karls-Universität Heidelberg
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Backs, Johannes, Prof. Dr. med. (Project leader)
Affiliation:
University Hospital Heidelberg
Complete address:
Universitätsklinikum Heidelberg
Abteilung für Kardiologie
Im Neuenheimer Feld 345
69120 Heidelberg
Phone:
+49 6221 56 37714
Fax:
+49 6221 56 5573
CV (PDF):

Fields of interest:

Cardiac molecular and cell biology, mouse genetics (conditional gene targeting), transcriptional control mechanisms, signal transduction, drug development.
Keywords:

Curriculum Vitae:

2007 
-
Present 
Junior Group Leader, Department of Cardiology, University of Heidelberg, Germany

2003 
-
2007 
PostDoc, UT Southwestern Medical School at Dallas, USA

2002 
-
2003 
PostDoc, Heidelberg University, Germany

1997 
-
2002 
MD, Department of Cardiology, Heidelberg University

1991 
-
1998 
Medical School, Universities of Giessen, Heidelberg and Freiburg, Germany

1990 
-
1991 
School of Biology, University of Bochum, Germany

Selected publications:

The gamma isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption (2010) Backs J, Stein P, Backs T, Duncan FE, Grueter CE, McAnally J, Qi X, Schultz RM, Olson EN Proc Natl Acad Sci U S A. 107(1):81-86

The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload (2009) Backs J, Backs T, Neef S, Kreusser MM, Lehmann LH, Patrick DM, Grueter CE, Qi X, Richardson JA, Hill JA, Katus HA, Bassel-Duby R, Maier LS, Olson EN Proc Natl Acad Sci U S A. 106(7):2342-2347

Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4 (2008) Backs J, Backs T, Bezprozvannaya S, McKinsey TA, Olson EN Mol Cell Biol. 28(10):3437-3445

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy (2006) Backs J, Song K, Bezprozvannaya S, Chang S, Olson EN J Clin Invest. 116(7):1853-1864

The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases (2006) Song K, Backs J, McAnally J, Qi X, Gerard RD, Richardson JA, Hill JA, Bassel-Duby R, Olson EN Cell. 125(3):453-466