Ruprecht-Karls-Universität Heidelberg
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Bading, Hilmar, Prof. Dr. (Project leader)
Affiliation:
Interdisciplinary Center for Neurosciences (IZN)
Complete address:
Neurobiology Institute
Interdisciplinary Center for Neurosciences (IZN)
Im Neuenheimer Feld 364
69120 Heidelberg
Phone:
+49 6221-54 8218
Fax:
+49 6221-54 6700
CV (PDF):

Fields of interest:

Neuronal signaling, nuclear calcium, gene regulation, neuronal plasticity, activity-dependent survival.
Keywords:

Curriculum Vitae:

2001 
-
Present 
Professor (C4) of Neurobiology, Director Neurobiology Institute, Interdisciplinary Center for Neurosciences (IZN), Heidelberg University

1993 
-
2001 
Group Leader at the MRC Laboratory of Molecular Biology, Cambridge, England

1989 
-
1992 
Harvard Medical School, Boston, USA, post-doctoral research in the Department of Microbiology and Molecular Genetics, Prof. Michael E. Greenberg

1985 
-
1989 
Max Planck Institut für molekulare Genetik, Berlin, post-doctoral research

1984 
-
 
MD (Dr. med.)

1981 
-
1984 
Max Planck Institut für medizinische Forschung, Heidelberg

1978 
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1984 
Heidelberg University (Humanmedizin)

Selected publications:

Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity. (2009) Zhang SJ, Zou M, Lu L, Lau D, Ditzel DA, Delucinge-Vivier C, Aso Y, Descombes P, Bading H. PLoS Genet. Aug;5(8):e1000604.

Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death. (2007) Zhang, SJ, Steijaert, MN, Lau, D, Schütz, G, Delucinge-Vivier, C, Descombes, P, and Bading, H Neuron 53, 549-562.

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways (2002) Hardingham GE, Fukunaga Y, Bading H Nat Neurosci 5: 405-414

A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication (2001) Hardingham GE, Arnold FJ, Bading H Nat Neurosci 4: 565-566

Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity (2001) Hardingham GE, Arnold FJ, Bading H Nat Neurosci 4: 261-267

Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels (1999) Hardingham GE, Chawla S, Cruzalegui FH, Bading H Neuron 22: 789-798

CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV (1998) Chawla S, Hardingham GE, Quinn DR, Bading H Science 281: 1505-1509

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression (1997) Hardingham GE, Chawla S, Johnson CM, Bading H Nature 385: 260-265

Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways (1993) Bading H, Ginty DD, Greenberg ME Science 260: 181-186

Stimulation of protein tyrosine phosphorylation by NMDA receptor activation (1991) Bading H, Greenberg ME Science 253: 912-914