Ruprecht-Karls-Universität Heidelberg
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Publications by HBIGS PhD students:

Publications in 2017

Boehler S, Lörracher AK, Schubert J, Braunbeck T (2017) Comparative live-imaging of in vivo EROD (ethoxyresorufin-O-deethylase) induction in zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) embryos after exposure to PAHs and river sediment extracts. Sci Total Environ, 621, 827-838

Koch MA, Michling F, Walther A, Huang XC, Tewes L, Müller C (2017) Early-Mid Pleistocene genetic differentiation and range expansions as exemplified by invasive Eurasian Bunias orientalis (Brassicaceae) indicates the Caucasus as key region. Sci Rep, 7, 1, 16764

Martins LR, Bung RK, Koch S, Richter K, Schwarzmüller L, Terhardt D, Kurtulmus B, Niehrs C, Rouhi A, Lohmann I, Pereira G, Fröhling S, Glimm H, Scholl C (2017) Stk33 is required for spermatid differentiation and male fertility in mice. Dev Biol, doi: 10.1016/j.ydbio.2017.11.007

Kolinko S, Wu YW, Tachea F, Denzel E, Hiras J, Gabriel R, Bäcker N, Chan LJG, Eichorst SA, Frey D, Chen Q, Azadi P, Adams PD, Pray TR, Tanjore D, Petzold CJ, Gladden JM, Simmons BA, Singer SW (2017) A bacterial pioneer produces cellulase complexes that persist through community succession. Nat Microbiol, doi: 10.1038/s41564-017-0052-z

Stanley CE*, Shrivastava J*, Brugman R, Heinzelmann E, van Swaay D, Grossmann G (*equal contribution) (2017) Dual-flow-RootChip reveals local adaptations of roots towards environmental asymmetry at the physiological and genetic levels. New Phytol, doi: 10.1111/nph.14887

Carroni M, Franke KB, Maurer M, Jäger J, Hantke I, Gloge F, Linder D, Gremer S, Turgay K, Bukau B, Mogk A (2017) Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, doi: 10.7554/eLife.30120

Pollmann J, Götz JJ, Rupp D, Strauss O, Granzin M, Grünvogel O, Mutz P, Kramer C, Lasitschka F, Lohmann V, Björkström NK, Thimme R, Bartenschlager R, Cerwenka A (2017) Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis. J Hepatol, doi: 10.1016/j.jhep.2017.10.021

Goganau I, Sandner B, Weidner N, Fouad K, Blesch A (2017) Depolarization and electrical stimulation enhance in vitro and in vivo sensory axon growth after spinal cord injury. Exp Neurol, 300, 247-258

Mildenberger I, Bunse L, Ochs K, Platten M (2017) The promises of immunotherapy in gliomas. Curr Opin Neurol, doi: 10.1097/WCO.0000000000000491

Sedaghat-Hamedani F, Haas J, Zhu F, Geier C, Kayvanpour E, Liss M, Lai A, Frese K, Pribe-Wolferts R, Amr A, Li DT, Samani OS, Carstensen A, Bordalo DM, Müller M, Fischer C, Shao J, Wang J, Nie M, Yuan L, Haßfeld S, Schwartz C, Zhou M, Zhou Z, Shu Y, (2017) Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy. Eur Heart J, doi: 10.1093/eurheartj/ehx545

Abu El Maaty MA, Wölfl S (2017) Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy Int J Mol Sci, 18, 10

Leibing T, Géraud C, Augustin I, Boutros M, Augustin HG, Okun JG, Langhans CD, Zierow J, Wohlfeil SA, Olsavszky V, Schledzewski K, Goerdt S, Koch PS (2017) Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice. Hepatology, doi: 10.1002/hep.29613

Karakatsani A, Marichal N, Urban S, Kalamakis G, Ghanem A, Schick A, Zhang Y, Conzelmann KK, Rüegg MA, Berninger B, de Almodovar CR, Gascón S, Kröger S (2017) Neuronal LRP4 regulates synapse formation in the developing CNS. Development, doi: 10.1242/dev.150110

Dong Y, Silbermann M, Speiser A, Forieri I, Linster E, Poschet G, Allboje Samami A, Wanatabe M, Sticht C, Teleman AA, Deragon JM, Saito K, Hell R, Wirtz M (2017) Sulfur availability regulates plant growth via glucose-TOR signaling. Nat Commun, 8, 1, 1174

Pollmann J, Götz JJ, Rupp D, Strauss O, Granzin M, Grünvogel O, Mutz P, Kramer C, Lasitschka F, Lohmann V, Björkström NK, Thimme R, Bartenschlager R, Cerwenka A (2017) Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis. J Hepatol, doi: 10.1016/j.jhep.2017.10.021

Preissler S, Rohland L, Yan Y, Chen R, Read RJ, Ron D (2017) AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, doi: 10.7554/eLife.29428

Lauer AN, Tenenbaum T, Schroten H, Schwerk C (2017) The Diverse Cellular Responses of the Choroid Plexus during Infection of the Central Nervous System Am J Physiol Cell Physiol, doi: 10.1152/ajpcell.00137.2017

Warnefors M, Mössinger K, Halbert J, Studer T, VandeBerg JL, Lindgren I, Fallahshahroudi A, Jensen P, Kaessmann H (2017) Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation. Genome Res, doi: 10.1101/gr.225391.117

Hohmann N, Koch MA (2017) An Arabidopsis introgression zone studied at high spatio-temporal resolution: interglacial and multiple genetic contact exemplified using whole nuclear and plastid genomes. BMC Genomics, 18, 1, 810

Wohlfarth C, Schmitteckert S, Härtle JD, Houghton LA, Dweep H, Fortea M, Assadi G, Braun A, Mederer T, Pöhner S, Becker PP, Fischer C, Granzow M, Mönnikes H, Mayer EA, Sayuk G, Boeckxstaens G, ...Rappold GA, Martinez C, Niesler B (2017) miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome. Sci Rep, 7, 1, 14680

Gorel A, Motomura K, Fukuzawa H, Doak RB, Grünbein ML, Hilpert M, Inoue I, Kloos M, Kovácsová G, Nango E, Nass K, Roome CM, Shoeman RL, Tanaka R, Tono K, Joti Y, Yabashi M, Iwata S, Foucar L, Ueda K, Barends TRM, Schlichting I (2017) Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability. Nat Commun, 8, 1, 1170

Fang T, Kasbi K, Rothe S, Aziz W, Giese KP (2017) Age-dependent changes in autophosphorylation of alpha calcium/calmodulin dependent kinase II in hippocampus and amygdala after contextual fear conditioning. Brain Res Bull., 134, 18-23

Colucci S, Pagani A, Pettinato M, Artuso I, Nai A, Camaschella C, Silvestri L. (2017) The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes. Blood, doi: 10.1182/blood-2017-04-780692

Linciano P, Dawson A, Pöhner I, Costa DM, Sá MS, Cordeiro-da-Silva A, Luciani R, Gul S, Witt G, Ellinger B et al. (2017) Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. ACS Omega, 2, 5666-5683

Dräger NM, Nachman E, Winterhoff M, Brühmann S, Shah P, Katsinelos T, Boulant S, Teleman AA, Faix J, Jahn TR (2017) Bin1 directly remodels actin dynamics through its BAR domain. EMBO Rep, doi: 10.15252/embr.201744137

Jäschke A, Coulibaly B, Remarque EJ, Bujard H, Epp C (2017) Merozoite surface protein-1 from P. falciparum is a major target of opsonizing antibodies in individuals with acquired immunity against malaria. Clin Vaccine Immunol, doi: 10.1128/CVI.00155-17

Wang X, Valls A, Schermann G, Shen Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L, Jain RK, Mazzone M, Schmidt T, Fischer T, Halder G, Ruiz de Almodóvar C (2017) YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis. Dev Cell, 42, 5, 462-478

Tonn N, Greb T (2017) Radial plant growth. Curr Biol, 27, 17, 878

Panecka-Hofman J, Pöhner I, Spyrakis F, Zeppelin T, Di Pisa F, Dello Iacono L, Bonucci A, Quotadamo A, Venturelli A, Mangani S, Costi MP and Wade RC (2017) Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors. Biochim Biophys Acta, doi: 10.1016/j.bbagen.2017.09.012

Bucher M, Jones VAS, Hambleton EA, Guse A (2017) Microinjection to deliver protein and mRNA into zygotes of the cnidarian endosymbiosis model Aiptasia sp. bioRXiv, doi:

Stanifer ML, Kischnick C, Rippert A, Albrecht D, Boulant S (2017) Reovirus inhibits interferon production by sequestering IRF3 into viral factories. Sci Rep, 7, 1, 10873

Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M (2017) Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J, 36, 18, 2770-2789

Palanisamy N, Akaberi D, Lennerstrand J (2017) Protein backbone flexibility pattern is evolutionarily conserved in the Flaviviridae family: a case of NS3 protease in Flavivirus and Hepacivirus. Mol Phylogenet Evol, doi: 10.1016/j.ympev.2017.09.015

Seleit A, Krämer I, Riebesehl BF, Ambrosio EM, Stolper JS, Lischik CQ, Dross N, Centanin L (2017) Neural stem cells induce the formation of their physical niche during organogenesis. Elife, doi: 10.7554/eLife.29173

Sprengel R, Eltokhi A, Single FN (2017) Gene Targeted Mice with Conditional Knock-In (-Out) of NMDAR Mutations. Methods Mol Biol, 1677, 201-230

Jana Tegethoff, Roland Bischoff , Sawsan Saleh , Biljana Blagojevic , Karl-Heinz Merz and Xinlai Cheng (2017) Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC Molecules 2017, 22(9), 1546

Luque Molina I, Khatri P, Schmidt-Edelkraut U, Simeonova IK, Hölzl-Wenig G, Mandl C, Ciccolini F (2017) Bone Morphogenetic Protein Promotes Lewis X Stage-Specific Embryonic Antigen 1 Expression Thereby Interfering with Neural Precursor and Stem Cell Proliferation. Stem Cells, doi: 10.1002/stem.2701

Olsavszky V, Ulbrich F, Singh S, Diett M, Sticht C, Schmid CD, Zierow J, Wohlfeil SA, Schledzewski K, Dooley S, Gaitantzi H, Breitkopf-Heinlein K, Géraud C, Goerdt S, Koch PS (2017) GATA4 and LMO3 balance angiocrine signaling and autocrine inflammatory activation by BMP2 in liver sinusoidal endothelial cells. Gene / 627:491-499

Cigler M*, Müller TG*, Horn-Ghetko D, von Wrisberg MK1, Fottner M, Goody RS, Itzen A, Müller MP, Lang K (*equal contribution) (2017) Proximity-triggered covalent stabilization of low-affinity protein complexes in vitro and in vivo Angew Chem Int Ed Engl, doi: 10.1002/anie.201706927

Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, Lohmann V, Dalpke AH (2017) Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells. Front Immunol, 8, 1238

Mugo E, Clayton C (2017) Expression of the RNA-binding protein RBP10 promotes the bloodstream-form differentiation state in Trypanosoma brucei. PLoS Pathog, 13, 8, e1006560

Grosse S, Penaud-Budloo M, Herrmann AK, Börner K, Fakhiri J, Laketa V, Krämer C, Wiedtke E, Gunkel M, Ménard L, Ayuso E, Grimm D (2017) Relevance of assembly-activating protein for Adeno-associated virus vector production and capsid protein stability in mammalian and insect cells. J Virol, doi: 10.1128/JVI.01198-17

Salz M, Häberle S, Hoffmann J, Enk AH, Hadaschik EN (2017) Elevated IL-31 serum levels in bullous pemphigoid patients correlate with eosinophil numbers and are associated with BP180-IgE. J Dermatol Sci, doi: 10.1016/j.jdermsci.2017.07.019

Acharya S, Hartmann M, Erhardt S (2017) Chromatin-associated noncoding RNAs in development and inheritance. Wiley Interdiscip Rev RNA, doi: 10.1002/wrna.1435

Garcia Del Arco A, Erhardt S (2017) Post-translational Modifications of Centromeric Chromatin. Prog Mol Subcell Biol, 56, 213-231

Sá-Moura B, Kornprobst M, Kharde S, Ahmed YL, Stier G, Kunze R, Sinning I, Hurt E (2017) Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome. PLoS One, 12, 8, e0183272

Glomstad B, Sørensen L, Liu J, Shen M, Zindler F, Jenssen BM, Booth AM. (2017) Evaluation of methods to determine adsorption of polycyclic aromatic hydrocarbons to dispersed carbon nanotubes. Environ Sci Pollut Res Int, doi: 10.1007/s11356-017-9953-x

Caicedo JC, Cooper S, Heigwer F, Warchal S, Qiu P, Molnar C, Vasilevich AS, Barry JD, Bansal HS, Kraus O, Wawer M, Paavolainen L, Herrmann MD, Rohban M, Hung J, Hennig H, Concannon J, Smith I, Clemons PA, Singh S, Rees P, Horvath P, Linington RG, Car (2017) Data-analysis strategies for image-based cell profiling. Nature Methods, 14, 9, 849-863

Maekawa H, Neuner A, Rüthnick D, Schiebel E, Pereira G, Kaneko Y (2017) Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha. Elife, doi: 10.7554/eLife.24340

Bunina D, Štefl M, Huber F, Khmelinskii A, Meurer M, Barry JD, Kats I, Kirrmaier D, Huber W, Knop M (2017) Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities. Nucleic Acids Res, doi: 10.1093/nar/gkx737

Meder B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Frese K, Lai A, Nietsch R, Scheiner C, Mester S, Martins Bordalo D, Amr A, Dietrich C, Pils D, Siede D, Hund H, Bauer AS, Holzer DB, Ruhparwar A, Mueller-Hennessen M, Weichenhan D, Plass C, Weis TM, (2017) Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and A Novel Class of Biomarkers for Heart Failure. Circulation, doi: 10.1161/CIRCULATIONAHA.117.027355

Siede D, Rapti K, Gorska AA, Katus HA, Altmüller J, Boeckel JN, Meder B, Maack C, Völkers M, Müller OJ, Backs J, Dieterich C (2017) Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease. J Mol Cell Cardiol, doi: 10.1016/j.yjmcc.2017.06.015

Döring K, Ahmed N, Riemer T, Suresh HG, Vainshtein Y, Habich M, Riemer J, Mayer MP, O'Brien EP, Kramer G, Bukau B (2017) Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding. Cell, 170, 2, 298-311

Ochs K, Bunse L, Mildenberger I, Wick W, Platten M (2017) Immuntherapien bei Gliomen. Der Onkologe, DOI 10.1007/s00761-017-0258-y

Krüger F, Schumacher K (2017) Pumping up the volume - vacuole biogenesis in Arabidopsis thaliana. Semin Cell Dev Biol, doi: 10.1016/j.semcdb.2017.07.008

Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, Ruckdeschel T, Hasanov Z, Srivastava K, Hu J, Hertel S, Bartol A, Schlereth K, Augustin HG (2017) Pericyte-expressed Tie2 controls angiogenesis and vessel maturation. Nat Commun, 8, 16106

Strassburger K, Lorbeer FK, Lutz M, Graf F, Boutros M, Teleman AA (2017) Oxygenation and adenosine deaminase support growth and proliferation of ex vivo cultured Drosophila wing imaginal discs. Development, 144, 13, 2529-2538

Northcott PA,..., Huebschmann D,...Lichter P (2017) The whole-genome landscape of medulloblastoma subtypes. Nature, 547, 7663, 311-317

Tric M, Lederle M, Neuner L, Dolgowjasow I, Wiedemann P, Wölfl S, Werner T (2017) Optical biosensor optimized for continuous in-line glucose monitoring in animal cell culture. Anal Bioanal Chem, doi: 10.1007/s00216-017-0511-7

Lempp FA, Urban S (2017) Hepatitis Delta Virus: Replication Strategy and Upcoming Therapeutic Options for a Neglected Human Pathogen. Viruses, 9, 7

Shah PNM, Stanifer ML, Höhn K, Engel U, Haselmann U, Bartenschlager R, Kräusslich HG, Krijnse-Locker J, Boulant S (2017) Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network. Cell Microbiol, doi: 10.1111/cmi.12765

Xu HT, Colby-Germinario SP, Hassounah SA, Fogarty C, Osman N, Palanisamy N, Han Y, Oliveira M, Quan Y, Wainberg MA. (2017) Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication. Sci Rep. 2017 Jul 24;7(1):6345. doi: 10.1038/s41598-017-06612-2.

Schaller T, Bulli L, Pollpeter D, Betancor G, Kutzner J, Apolonia L, Herold N, Burk R, Malim MH (2017) Effects of the inner nuclear membrane proteins SUN1/UNC-84A and SUN2/UNC-84B on the early steps of HIV-1 infection. J Virol, doi: 10.1128/JVI.00463-17

Dabiri Y, Kalman S, Gürth CM, Kim JY, Mayer V, Cheng X (2017) The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells. Sci Rep, 7, 1, 5423

Kossack M, Hein S, Juergensen L, Siragusa M, Benz A, Katus HA, Most P, Hassel D (2017) Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J Mol Cell Cardiol, 108, 95-105

Kmiecik SW, Krzyścik MA, Filip-Psurska B, Wietrzyk J, Boratyński J, Goszczyński TM (2017) Methotrexate and epirubicin conjugates as potential antitumor drugs Postepy Hig Med Dosw (Online), 71, 0, 618-623

Weinmann J, Grimm D (2017) Next-generation AAV vectors for clinical use: an ever-accelerating race. Virus Genes, doi: 10.1007/s11262-017-1502-7

Häberle S, Raker V, Haub J, Kim YO, Weng SY, Yilmaz OK, Enk A, Steinbrink K, Schuppan D, Hadaschik EN (2017) Regulatory T cell deficient scurfy mice exhibit a Th2/M2-like inflammatory response in the skin. J Dermatol Sci, doi: 10.1016/j.jdermsci.2017.07.001

Lauinger L, Li J, Shostak A, Cemel IA, Ha N, Zhang Y, Merkl PE, Obermeyer S, Stankovic-Valentin N, Schafmeier T, Wever WJ, Bowers AA, Carter KP, Palmer AE, Tschochner H, Melchior F, Deshaies RJ, Brunner M, Diernfellner A (2017) Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases. Nat Chem Biol, 13, 7, 709-714

de Sena Cortabitarte A, Degenhardt F, Strohmaier J, Lang M, Weiss B, Roeth R, Giegling I, Heilmann-Heimbach S, Hofmann A, Rujescu D, Fischer C, Rietschel M, Nöthen MM, Rappold GA, Berkel S (2017) Investigation of SHANK3 in schizophrenia. Am J Med Genet B Neuropsychiatr Genet, 174, 4, 390-398

Weyer FA, Gumiero A, Lapouge K, Bange G, Kopp J, Sinning I (2017) Structural basis of HypK regulating N-terminal acetylation by the NatA complex. Nat Commun, 8, 15726

Schopp IM, Amaya Ramirez CC, Debeljak J, Kreibich E, Skribbe M, Wild K, Béthune J (2017) Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes. Nat Commun, 8, 15690

Giessler KM, Kleinheinz K, Huebschmann D, Balasubramanian GP, Dubash TD, Dieter SM, Siegl C, Herbst F, Weber S, Hoffmann CM, Fronza R, Buchhalter I, Paramasivam N, Eils R, Schmidt M, von Kalle C, Schneider M, Ulrich A, Scholl C, Fröhling S, Weichert (2017) Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer. J Exp Med, doi: 10.1084/jem.20162017.

Mücksch F, Laketa V, Müller B, Schultz C, Kräusslich HG (2017) Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring. Elife, doi: 10.7554/eLife.25287

Abu El Maaty MA, Strassburger W, Qaiser T, Dabiri Y, Wölfl S (2017) Differences in p53 status significantly influence the cellular response and cell survival to 1,25-Dihydroxyvitamin D3-Metoformin cotreatment in colorectal cancer cells. Mol Carcinog, doi: 10.1002/mc.22696

Zatorska E, Gal L, Schmitt J, Bausewein D, Schuldiner M, Strahl S (2017) Cellular Consequences of Diminished Protein O-Mannosyltransferase Activity in Baker's Yeast. Int J Mol Sci, 18, 6

Gandla J, Lomada SK, Lu J, Kuner R, Bali KK (2017) miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels. Pain, doi: 10.1097/j.pain.0000000000000971

Abu El Maaty MA, Alborziniaa H, Khana SJ, Michael Büttner M, Wölfl S (2017) 1,25(OH)2D3 Disrupts glucose metabolism in prostate cancer cells leading to a truncation of the tca cycle and inhibition of txnip expression Biochim Biophys Acta,

Mugo E, Egler F, Clayton C (2017) Conversion of procyclic-form Trypanosoma brucei to the bloodstream form by transient expression of RBP10. Mol Biochem Parasitol, doi: 10.1016/j.molbiopara.2017.06.009

Garcia-Knight MA, Nduati E, Hassan AS, Nkumama I, Etyang TJ, Hajj NJ, Gambo F, Odera D, Berkley JA, Rowland-Jones SL, Urban B. (2017) Cytomegalovirus viraemia is associated with poor growth and T-cell activation with an increased burden in HIV-exposed uninfected infants. AIDS, doi: 10.1097/QAD.0000000000001568

Rüthnick D, Neuner A, Dietrich F, Kirrmaier D, Engel U, Knop M, Schiebel E (2017) Characterization of spindle pole body duplication reveals a regulatory role for nuclear pore complexes. J Cell Biol, doi: 10.1083/jcb.201612129

Ochs K, Ott M, Bunse T, Sahm F, Bunse L, Deumelandt K, Sonner JK, Keil M, von Deimling A, Wick W, Platten M (2017) K27M-mutant histone-3 as a novel target for glioma immunotherapy. OncoImmunology, DOI: 10.1080/2162402X.2017.1328340

Graf M, Bonetti D, Lockhart A, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT, Luke B. (2017) Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle. Cell, 170, 1, 72-85

Rauscher B, Valentini E, Hardeland U, Boutros M (2017) Phenotype databases for genetic screens in human cells. J Biotechnol, doi: 10.1016/j.jbiotec.2017.06.008

Hirth M, Gandla J, Kuner R (2017) A checkpoint to pain. Nat Neurosci, 20, 897

Jin Y, Patel PH, Kohlmaier A, Pavlovic B, Zhang C, Edgar BA (2017) Intestinal Stem Cell Pool Regulation in Drosophila Stem Cell Reports; 8(6):1479-1487

Bender M, Schwind L, Grundmann D, Martin M, Klotz M, Götz C, Montenarh M, Schäfer KH (2017) Impact of protein kinase CK2 inhibitors on proliferation and differentiation of neural stem cells. Heliyon, doi: 10.1016/j.heliyon.2017.e00318

Pagani A, Colucci S, Bocciardi R, Bertamino M, Dufour C, Ravazzolo R, Silvestri L, Camaschella C (2017) A new form of IRIDA due to combined heterozygous mutations of TMPRSS6 and ACVR1A encoding the BMP receptor ALK2. Blood, doi: 10.1182/blood-2017-03-773481

Palanisamy N, Lennerstrand J. (2017) Computational Prediction of Usutu Virus E Protein B Cell and T Cell Epitopes for Potential Vaccine Development. Scand J Immunol, 85, 5, 350-364

Chen NP, Uddin B, Hardt R, Ding W, Panic M, Lucibello I, Kammerer P, Ruppert T, Schiebel E (2017) Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm. Proc Natl Acad Sci U S A, doi: 10.1073/pnas.1619356114

Sahm F*, Toprak UH*, Huebschmann D*, Kleinheinz K, Buchhalter I, Sill M, Stichel D, Schick M, Bewerunge-Hudler M, Schrimpf D, Zadeh G, Aldape K, Herold-Mende C, Beck K, Staszewski O, Prinz M, Harosh CB, Eils R,.., von Deimling A (*equal contribution) (2017) Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature. Acta Neuropathol, doi: 10.1007/s00401-017-1715-9

Dasanna AK, Lansche C, Lanzer M, Schwarz US (2017) Rolling Adhesion of Schizont Stage Malaria-Infected Red Blood Cells in Shear Flow. Biophys J, 112, 9, 1908-1919

Xiang J, Bandura J, Zhang P, Jin Y, Reuter H, Edgar BA (2017) EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration. Nat Commun, 8, 15125

Nötzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S (2017) The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells. Sci Rep, 7, 1, 2265

Chen S., Tisch N., Kegel M., Yerbes R., Hermann R., Hudalla H., Zuliani C., Gülcüler GS., Zwadlo K., von Engelhardt J., Ruiz de Almodóvar C., Martin-Villalba A. (2017) CNS Macrophages Control Neurovascular Development via CD95L. Cell Reports,Volume 19, Issue 7/Pages 1378–1393

Moreau CA, Bhargav SP, Kumar H, Quadt KA, Piirainen H, Strauss L, Kehrer J, Streichfuss M, Spatz JP, Wade RC, Kursula I, Frischknecht F (2017) A unique profilin-actin interface is important for malaria parasite motility. PLoS Pathog, 13, 5, e1006412

Santos JM, Egarter S, Zuzarte-Luís V, Kumar H, Moreau CA, Kehrer J, Pinto A, Costa MD, Franke-Fayard B, Janse CJ, Frischknecht F, Mair GR (2017) Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts. Elife, doi: 10.7554/eLife.24109

Selvaraj D, Hirth M, Gandla J, Kuner R (2017) Modelling pain associated with pancreatic ductal adenocarcinoma in mice. Pain, doi: 10.1097/j.pain.0000000000000956

Müller T, Winter D (2017) Systematic Evaluation of Protein Reduction and Alkylation Reveals Massive Unspecific Side Effects by Iodine-containing Reagents Mol Cell Proteomics, doi: 10.1074/mcp.M116.064048

Scheeder C, Heigwer F, Boutros M (2017) HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens.
Bioinformatics, doi: 10.1093/bioinformatics/btx319

Nwosu ZC, Megger DA, Hammad S, Sitek B, Roessler S, Ebert MP, Meyer C, Dooley S (2017) Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol, 4, 2, 303-323

Kovácsová G, Grünbein ML, Kloos M, Barends TRM, Schlesinger R, Heberle J, Kabsch W, Shoeman RL, Doak RB, Schlichting I (2017) Viscous hydrophilic injection matrices for serial crystallography. IUCrJ, 4, 4, 400-410

Begas P*, Liedgens L*, Moseler A, Meyer AJ, Deponte M (*equal contribution) (2017) Glutaredoxin catalysis requires two distinct glutathione interaction sites. Nat Commun, 8, 14835

Garg J, Feng YX, Jansen SR, Friedrich J, Lezoualc'h F, Schmidt M, Wieland T (2017) Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation. Oncotarget, doi pending

Pervolaraki K, Stanifer ML, Münchau S, Renn LA, Albrecht D, Kurzhals S, Senis E, Grimm D, Schröder-Braunstein J, Rabin RL, Boulant S (2017) Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut. Front Immunol, 8, 459

Klingenberg M, Matsuda A, Diederichs S, Patel T (2017) Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets. J Hepatol, doi: 10.1016/j.jhep.2017.04.009

Sakin V, Hanne J, Dunder J, Anders-Össwein M, Laketa V, Nikić I, Kräusslich HG, Lemke EA, Müller B (2017) A Versatile Tool for Live-Cell Imaging and Super-Resolution Nanoscopy Studies of HIV-1 Env Distribution and Mobility. Cell Chem Biol, doi: 10.1016/j.chembiol.2017.04.007

Lindner R, Hartmann E, Tarnawski M, Winkler A, Frey D, Reinstein J, Meinhart A, Schlichting I (2017) Photoactivation mechanism of a bacterial light-regulated adenylyl cyclase. J Mol Biol, doi: 10.1016/j.jmb.2017.03.020

Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel R L (2017) Stress-induced protein S-glutathionylation and S-trypanothionylation in African trypanosomes – a quantitative redox proteome and thiol analysis Antioxid Redox Signal, doi: 10.1089/ars.2016.6947

Di Pisa F, Landi G, Dello Iacono L, Pozzi C, Borsari C, Ferrari S, Santucci M, Santarem N, Cordeiro-da-Silva A, Moraes CB, Alcantara LM, Fontana V, Freitas-Junior LH, Gul S, Kuzikov M, Behrens B, Pöhner I, Wade RC, Costi MP, Mangani S (2017) Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity. Molecules, 22, 3, 426

Blank MF, Chen S, Poetz F, Schnölzer M, Voit R, Grummt I (2017) SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res, 45, 5, 2675-2686

Daturpalli S, Knieß RA, Lee CT, Mayer MP. (2017) Large rotation of the N-terminal domain of Hsp90 is important for interaction with some but not all client proteins. J Mol Biol, doi: 10.1016/j.jmb.2017.03.025

Giaretta S, Prasad D, Forieri I, Vamerali T, Trentin AR, Wirtz M, Hell R, Masi A (2017) Apoplastic gamma-glutamyl transferase activity encoded by GGT1 and GGT2 is important for vegetative and generative development. Plant Physiol Biochem, 115, 44-56

Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C (2017) Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun, 8, 14583

Sütterlin T, Tsingos E, Bensaci J, Stamatas GN, Grabe N (2017) A 3D self-organizing multicellular epidermis model of barrier formation and hydration with realistic cell morphology based on EPISIM. Sci Rep, 7, 43472

Géraud C*, Koch PS*, Zierow J*, Klapproth K, Busch K, Olsavszky V, Leibing T, Demory A, Ulbrich F, Diett M, Singh S, Sticht C, Breitkopf-Heinlein K, Richter K, Karppinen SM, Pihlajaniemi T, Arnold B, Rodewald HR, Augustin HG, Schledzewski K, Goerdt S (2017) GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis. J Clin Invest, 127, 3, 1099-1114

Wallner ES, López-Salmerón V, Belevich I, Poschet G, Jung I, Grünwald K, Sevilem I, Jokitalo E, Hell R, Helariutta Y, Agustí J, Lebovka I, Greb T (2017) Strigolactone- and Karrikin-Independent SMXL Proteins Are Central Regulators of Phloem Formation. Curr Biol, doi: 10.1016/j.cub.2017.03.014

Comba P, Eisenschmidt A, Gahan LR, Herten DP, Nette G, Schenk G, Seefeld M (2017) Is CuII coordinated to patellamides inside Prochloron cells Chemistry - A European Journal

Hoffmann S, Schmitteckert S, Griesbeck A, Preiss H, Sumer S, Rolletschek A, Granzow M, Eckstein V, Niesler B, Rappold GA (2017) Comparative expression analysis of Shox2-deficient embryonic stem cell-derived sinoatrial node-like cells. Stem Cell Res, 21, 51-57

Yu Y, Oberlaender K, Bengtson CP, Bading H (2017) One nuclear calcium transient induced by a single burst of action potentials represents the minimum signal strength in activity-dependent transcription in hippocampal neurons. Cell Calcium, doi: 10.1016/j.ceca.2017.03.003.

Zhou-Suckow Z, Duerr J, Hagner M, Agrawal R, Mall MA (2017) Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases. Cell Tissue Res, 367, 3, 537-550

Banaeiyan AA, Theobald J, Paukštyte J, Wölfl S, Adiels CB, Goksör M (2017) Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication, 9, 1, 015014

Weiler SM, Pinna F, Wolf T, Lutz T, Geldiyev A, Sticht C, Knaub M, Thomann S, Bissinger M, Wan S, Rössler S, Becker D, Gretz N, Lang H, Bergmann F, Ustiyan V, Kalin TV, Singer S, Lee JS, Marquardt JU, Schirmacher P, Kalinichenko VV, Breuhahn K (2017) Induction of Chromosome Instability by Activation of Yes Associated Protein and Forkhead box M1 in Liver Cancer. Gastroenterology, doi: 10.1053/j.gastro.2017.02.018

Shi D, Tavhelidse T, Thumberger T, Wittbrodt J, Greb T (2017) Bifacial stem cell niches in fish and plants. Curr Opin Genet Dev, 45, 28-33

Ghanem A, Kitanovic A, Holzwarth J, Wölfl S (2017) Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress. Microbial Cell, 4, 2, 52 - 63

Hänggi K, Vasilikos L, Valls AF, Yerbes R, Knop J, Spilgies LM, Rieck K, Misra T, Bertin J, Gough PJ, Schmidt T, de Almodòvar CR, Wong WW. (2017) RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function. Cell Death Dis, 8, 2, e2588

Valls AF, Shen Y, Schmidt T (2017) A core of macrophages facilitates ovarian cancer metástasis. Perspective Transl Cancer Res, 6, Suppl 1, S189-S196.

Solís-López A, Kriebs U, Marx A, Mannebach S, Liedtke WB, Caterina MJ, Freichel M, Tsvilovskyy VV (2017) Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells. PLoS One, 12, 2, e0171366

Kumar R, Neuser N, Tyedmers J (2017) Hitchhiking vesicular transport routes to the vacuole: Amyloid recruitment to the Insoluble Protein Deposit (IPOD). Prion, 1-11

Franke KB, Bukau B, Mogk A (2017) Mutant Analysis Reveals Allosteric Regulation of ClpB Disaggregase. Front Mol Biosci, 4, 6

Toth K, Lill Y, Lehmann K, Gansen A, Langowski J (2017) How to Open a Nucleosome. Biophys J, 112, 3, 375a

Gansen A, Felekyan S, Lehmann K, Kühnemuth R, Zhang R, Tóth K, Seidel CAM, Langowski J (2017) Nucleosome Opening Kinetics and the Influence of Histone Modifications Studied by Single Molecule FRET. Biophys J, 112, 3, 217a

Lehmann K, Gansen A, Toth K, Langowski J (2017) Single Molecule Fluorescence Studies on Nucleosome Dynamics. Biophys J, 112, 3, 474a

Pande D, Madzokere E, Hartnady P, Kraberger S, Hadfield J, Rosario K, Jäschke A, Monjane AL, Owor BE, Dida MM, Shepherd DN, Martin DP, Varsani A, Harkins GW (2017) The role of Kenya in the trans-African spread of maize streak virusstrain A. Virus Res, 232, 69-76

Murungi LM, Sondén K, Odera D, Oduor LB, Guleid F, Nkumama IN, Otiende M, Kangoye DT, Fegan G, Färnert A, Marsh K, Osier FH (2017) Cord blood IgG and the risk of severe Plasmodium falciparum malaria in the first year of life. Int J Parasitol, 47, 2-3, 153-162

Nkumama IN, O'Meara WP, Osier FH (2017) Changes in Malaria Epidemiology in Africa and New Challenges for Elimination. Trends Parasito, 33, 2, 128-140

Sedlmeier G, Sleeman JP (2017) Extracellular regulation of BMP signaling: welcome to the matrix. Biochem Soc Trans, 45, 1, 173-181

Hänselmann S, Herten DP (2017) Single-Molecule Spectroscopy In: J. C. Lindon, G. E. Tranter, D. W. Koppenaal (Eds.): Encyclopedia of Spectroscopy and Spectrometry 4, Elsevier, 84–88. DOI: 10.1016/B978-0-12-409547-2.12093-1

Winz ML, Cahová H, Nübel G, Frindert J, Höfer K, Jäschke A (2017) Capture and sequencing of NAD-capped RNA sequences with NAD captureSeq. Nat Protoc, 12, 1, 122-149

Roth H, Magg V, Uch F, Mutz P, Klein P, Haneke K, Lohmann V, Bartenschlager R, Fackler OT, Locker N, Stoecklin G, Ruggieri A (2017) Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses. mBio, 8, 1, e02150-16

Weyer FA, Gumiero A, Gesé GV, Lapouge K, Sinning I (2017) Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex. Nat Struct Mol Biol, doi: 10.1038/nsmb.3349

Palanisamy N, Osman N, Ohnona F, Xu HT, Brenner B, Mesplède T, Wainberg MA. (2017) Does antiretroviral treatment change HIV-1 codon usage patterns in its genes: a preliminary bioinformatics study. AIDS Res Ther, 14, 1, 2

Herrmannsdörfer F, Flottmann B, Nanguneri S, Venkataramani V, Horstmann H, Kuner T, Heilemann M (2017) 3D d STORM Imaging of Fixed Brain Tissue. Methods Mol Biol, 1538, 169-184

Seleit A, Krämer I, Ambrosio E, Dross N, Engel U, Centanin L (2017) Sequential organogenesis sets two parallel sensory lines in medaka. Development, doi: 10.1242/dev.142752

Heinrich P, Petschick LL, Northcott GL, Tremblay LA, Ataria JM, Braunbeck T. (2017) Assessment of cytotoxicity, genotoxicity and 7-ethoxyresorufin-O-deethylase (EROD) induction in sediment extracts from New Zealand urban estuaries. Ecotoxicology, doi: 10.1007/s10646-016-1756-1

Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, Gruss OJ (2017) Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun, 8, 14090

Nguyen MT, Knieß RA, Daturpalli S, Le Breton L, Ke X, Chen X, Mayer MP (2017) Isoform-specific phosphorylation in human Hsp90β affects interaction with clients and the cochaperone Cdc37. J Mol Biol, doi: 10.1016/j.jmb.2017.01.011

Caydasi AK, Khmelinskii A, Duenas-Sanchez R, Kurtulmus B, Knop M, Pereira G (2017) Temporal and compartment-specific signals coordinate mitotic exit with spindle position. Nat Commun, 8, 14129

Abu El Maaty MA, Wölfl S (2017) Effects of 1,25(OH)₂D₃ on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents. Nutrients, 9, 1

Muthinja MJ, Ripp J, Hellmann JK, Haraszti T, Dahan N, Lemgruber L, Battista A, Schütz L, Fackler OT, Schwarz US, Spatz JP, Frischknecht F (2017) Microstructured Blood Vessel Surrogates Reveal Structural Tropism of Motile Malaria Parasites. Adv Healthc Mater, doi: 10.1002/adhm.201601178

Willemsen J, Wicht O, Wolanski JC, Baur N, Bastian S, Haas DA, Matula P, Knapp B, Meyniel-Schicklin L, Wang C, Bartenschlager R, Lohmann V, Rohr K, Erfle H, Kaderali L, Marcotrigiano J, Pichlmair A, Binder M (2017) Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siena Screening. Mol Cell, 65, 1–13

Hasanov Z, Ruckdeschel T, König C, Mogler C, Kapel SS, Korn C, Spegg C, Eichwald V, Wieland M, Appak S, Augustin HG (2017) Endosialin Promotes Atherosclerosis Through Phenotypic Remodeling of Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol, doi: 10.1161/ATVBAHA.116.308455

Klug D, Frischknecht F (2017) Motility precedes egress of malaria parasites from oocysts. Elife, doi: 10.7554/eLife.19157

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M (2017) SC83288 is a clinical development candidate for the treatment of severe malaria. Nat Commun, 8, 14193

Xing S, Mehlhorn DG, Wallmeroth N, Asseck LY, Kar R, Voss A, Denninger P, Schmidt VA, Schwarzländer M, Stierhof YD, Grossmann G, Grefen C (2017) Loss of GET pathway orthologs in Arabidopsis thaliana causes root hair growth defects and affects SNARE abundance. Proc Natl Acad Sci U S A, doi: 10.1073/pnas.1619525114

Hauser SL, ...Friedrich M,...Kappos, L (2017) Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis. N Engl J Med, 376, 3, 221-234

Pelzer P, Horstmann H, Kuner T (2017) Ultrastructural and Functional Properties of a Giant Synapse Driving the Piriform Cortex to Mediodorsal Thalamus Projection. Front Synaptic Neurosci, 9, 3