Ruprecht-Karls-Universität Heidelberg
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Publications by HBIGS PhD students:

Publications in 2018

Lawrence RE, Cho KF, Rappold R, Thrun A, Tofaute M, Kim DJ, Moldavski O, Hurley JH, Zoncu R (2018) A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold. Nat Cell Biol., 20, 9, 1052-1063

Durrieu L, Kirrmaier D, Schneidt T, Kats I, Raghavan S, Hufnagel L, Saunders TE, Knop M (2018) Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis. Mol Syst Biol, 14, 9, e8355

Gunzelmann J, Rüthnick D, Lin TC, Zhang W, Neuner A, Jäkle U, Schiebel E (2018) The microtubule polymerase Stu2 promotes oligomerization of the γ-TuSC for cytoplasmic microtubule nucleation. Elife, 7, e39932

Kurtulmus B, Yuan C, Schuy J, Neuner A, Hata S, Kalamakis G, Martin-Villalba A, Pereira G (2018) LRRC45 contributes to early steps of axoneme extension. J Cell Sci, doi: 10.1242/jcs.223594

Brillada C, Zheng J, Krüger F, Rovira-Diaz E, Askani JC, Schumacher K, Rojas-Pierce M (2018) Phosphoinositides control the localization of HOPS subunit VPS41, which together with VPS33 mediates vacuole fusion in plants. Proc Natl Acad Sci U S A, doi: 10.1073/pnas.1807763115

Frindert J, Zhang Y, Nübel G, Kahloon M, Kolmar L, Hotz-Wagenblatt A, Burhenne J, Haefeli WE, Jäschke A (2018) Identification, Biosynthesis, and Decapping of NAD-Capped RNAs in B. subtilis. Cell Rep, 24,7, 1890-1901

Friedrich M, Bunse L, Wick W, Platten M (2018) Perspectives of immunotherapy in isocitrate dehydrogenase-mutant gliomas. Curr Opin Oncol, doi: 10.1097/CCO.0000000000000478

Huck S, Bock J, Girardello J, Gauert M, Pul Ü (2018) Marker-free genome editing in Ustilago trichophora with the CRISPR-Cas9 technology. RNA Biol, 10, 1-7

Terrao M*, Marucha KK*, Mugo E, Droll D, Minia I, Egler F, Braun J, Clayton C (*equal contribution) (2018) The suppressive cap-binding complex factor 4EIP is required for normal differentiation. Nucleic Acids Res, doi: 10.1093/nar/gky733

Dong Y, Teleman A, Jedmowski C, Wirtz M, Hell R (2018) The Arabidopsis THADA homolog modulates TOR activity and cold acclimation. Plant Biol (Stuttg), doi: 10.1111/plb.12893

Atienzar-Aroca S, Serrano-Heras G, Valls AF, Ruiz de Almodovar C, Muriach M, Barcia JM, Garcia-Verdugo JM, Romero FJ, Sancho-Pelluz J (2018) Role of retinal pigment epithelium-derived exosomes and autophagy in new blood vessel formation. J Cell Mol Med, doi: 10.1111/jcmm.13730

Abu El Maaty MA, Dabiri Y, Almouhanna F, Blagojevic B, Theobald J, Büttner M, Wölfl S (2018) Activation of pro-survival metabolic networks by 1,25(OH)2D3 does not hamper the sensitivity of breast cancer cells to chemotherapeutics. Cancer Metab, 6, 11

Shiber A, Döring K, Friedrich U, Klann K, Merker D, Zedan M, Tippmann F, Kramer G, Bukau B (2018) Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling. Nature, doi: 10.1038/s41586-018-0462-y

Kempf G, Stjepanovic G, Sloan J, Hendricks A, Lapouge K, Sinning I (2018) The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane. Structure, doi: 10.1016/j.str.2018.07.008

Gutierrez-Triana JA*, Tavhelidse T*, Thumberger T*, Thomas I, Wittbrodt B, Kellner T, Anlas K, Tsingos E, Wittbrodt J (*equal contribution) (2018) Efficient single-copy HDR by 5' modified long dsDNA donors. Elife, 7, e39468

Bunse L, Pusch S,... Platten M (2018) Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate. Nat Med, doi.org/10.1038/s41591-018-0095-6

Herrmann AK, Grosse S, Börner K, Krämer C, Wiedtke E, Gunkel M, Grimm D (2018) Impact of the assembly-activating protein (AAP) on molecular evolution of synthetic Adeno-associated virus (AAV) capsids. Hum Gene Ther, doi: 10.1089/hum.2018.085

Senis E, Mosteiro L, Wilkening S, Wiedtke E, Nowrouzi A, Afzal S, Fronza R, Landerer H, Abad M, Niopek D, Schmidt M, Serrano M, Grimm D (2018) AAVvector-mediated in vivo reprogramming into pluripotency. Nat Commun, 9, 1, 2651

Rothe S, Prakash A, Tyedmers J (2018) The Insoluble Protein Deposit (IPOD) in Yeast. Front Mol Neurosci, 11, 237

Schürholz AK, Lopez-Salmeron V, Li Z, Forner J, Wenzl C, Gaillochet C, Augustin S, Vilches-Barro A, Fuchs M, Gebert M, Lohmann JU, Greb T, Wolf S (2018) A Comprehensive Toolkit for Inducible, Cell Type-Specific Gene Expression in Arabidopsis. Plant Physiol, doi: 10.1104/pp.18.00463

Schulte JT, Wierenga CJ, Bruining H (2018) Chloride transporters and GABA polarity in developmental, neurological and psychiatric conditions. Neurosci Biobehav Rev, 90, 260-271

Born D, Reuter L, Mersdorf U, Mueller M, Fischer MG, Meinhart A, Reinstein J (2018) Capsid protein structure, self-assembly, and processing reveal morphogenesis of the marine virophage mavirus. Proc Natl Acad Sci U S A, 115, 28, 7332-7337

Eltokhi A, Rappold G, Sprengel R (2018) Distinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants. Front Mol Neurosci, 11, 240

Straka T, Vita V, Prokshi K, Hörner SJ, Khan MM, Pirazzini M, Williams MPI, Hafner M, Zaglia T, Rudolf R (2018) Postnatal Development and Distribution of Sympathetic Innervation in Mouse Skeletal Muscle. Int J Mol Sci, 19, 7

Bogacz M, Krauth-Siegel RL (2018) Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death. Elife, 7, e37503

Janocha D, Lohmann JU (2018) From signals to stem cells and back again Curr Opin Plant Biol, 45, 136-142

Shan S, Chatterjee A, Qiu Y, Hammes HP, Wieland T, Feng Y (2018) O-GlcNAcylation of FoxO1 mediates nucleoside diphosphate kinase B deficiency induced endothelial damage Scientific Reports 8, 10581

Weigt D, Sammour DA, Ulrich T, Munteanu B, Hopf C (2018) Automated analysis of lipid drug-response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping. Sci Rep, 8, 1, 11260

Ahmed YL, Schleich S, Bohlen J, Mandel N, Simon B, Sinning I, Teleman AA (2018) DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. PLoS Biol, 16, 6, e2005160

Glomstad B, Zindler F, Jenssen BM, Booth AM (2018) Dispersibility and dispersion stability of carbon nanotubes in synthetic aquatic growth media and natural freshwater. Chemosphere, 201, 269-277

Sultan CS, Saackel A, Stank A, Fleming T, Fedorova M, Hoffmann R, Wade RC, Hecker M, Wagner AH (2018) Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol, 16, 113-122

Montgomery ST, Dittrich AS, Garratt LW, Turkovic L, Frey DL, Stick SM, Mall MA, Kicic A; AREST CF (2018) Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis. J Cyst Fibros, doi: 10.1016/j.jcf.2018.05.006

Cho H., Cho HS., Nam H., Jo H., Yoon J., Park C., Dang TVT., Kim E., Jeong J., Park S., Wallner ES., Youn H., Park J., Jeon J., Ryu H., Greb T., Choi K., Lee Y., Jang SK., Ban C., Hwang I (2018) Translational control of phloem development by RNA G-quadruplex-JULGI determines plant sink strength. Nat Plants, 4, 6, 376-390

Foerster JM, Pöhner I, Ullmann GM (2018) MCMap - A Computational Tool for Mapping Energy Landscapes of Transient Protein-Protein Interactions. ACS Omega, 3, 6, 6465-6475

Cordas Dos Santos DM, Eilers J, Sosa Vizcaino A, Orlova E, Zimmermann M, Stanulla M, Schrappe M, Börner K, Grimm D, Muckenthaler MU, Kulozik AE, Kunz JB (2018) MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB. BMC Cancer, 18, 1, 663

Linster E, Wirtz M (2018) N-terminal acetylation -an Essential Protein Modification Emerges as an Important Regulator of Stress Responses. J Exp Bot, doi: 10.1093/jxb/ery241

Streciwilk W, Terenzi A, Cheng X, Hager L, Dabiri Y, Prochnow P, Bandow JE, Wölfl S, Keppler BK, Ott I (2018) Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction. Eur J Med Chem, 156, 148-161

Heinrich P, Braunbeck T (2018) Genetically engineered zebrafish liver (ZF-L) cells as an in vitro source for zebrafish acetylcholinesterase (zfAChE) for the use in AChE inhibition assays. Toxicol In Vitro, 52, 52-59

Specht S, Liedgens L, Duarte M, Stiegler A, Wirth U, Eberhardt M, Tomás A, Hell K, Deponte M (2018) A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast. Redox Biol, 15, 363-374

Kats I, Khmelinskii A, Kschonsak M, Huber F, Knieß R, Bartosik A, Knop M (2018) Mapping degradation signals and pathways in a eukaryotic N-terminome. Mol Cell, 70, 3, 488-501

Tsvilovskyy V, Solís-López A, Schumacher D, Medert R, Roers A, Kriebs U, Freichel M (2018) Deletion of Orai2 augments endogenous CRAC currents and degranulation in mast cells leading to enhanced anaphylaxis. Cell Calcium, 71, 24-33

Rüthnick D, Schiebel E (2018) Duplication and Nuclear Envelope Insertion of the Yeast Microtubule Organizing Centre, the Spindle Pole Body. Cells, 7, 5

Speiser A, Silbermann M, Dong Y, Haberland S, Uslu VV, Wang S, Bangash SAK, Reichelt M, Meyer AJ, Wirtz M, Hell R (2018) Sulfur partitioning between glutathione and protein synthesis determines plant growth. Plant Physiol, doi: 10.1104/pp.18.00421

Hoffmann A, Dege T, Kunze R, Ernst AS, Lorenz H, Böhler LI, Korff T, Marti HH, Heiland S, Bendszus M, Helluy X, Pham M (2018) Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules. Stroke, doi: 10.1161/STROKEAHA.118.020927

Öztürk MA, Cojocaru V, Wade RC (2018) Dependence of Chromatosome Structure on Linker Histone Sequence and Posttranslational Modification. Biophys J, doi: 10.1016/j.bpj.2018.04.034

Katsinelos T, Zeitler M, Dimou E, Karakatsani A, Müller HM, Nachman E, Steringer JP, Ruiz de Almodovar C, Nickel W, Jahn TR (2018) Unconventional Secretion Mediates the Trans-cellular Spreading of Tau. Cell Rep, 23, 7, 2039-2055

Warsow G*, Huebschmann D*, ...Schlesner M, Sültmann H, Hohenfellner M, Duensing S (*equal contribution) (2018) Genomic features of renal cell carcinoma with venous tumor thrombus. Sci Rep, 8, 1, 7477

Szoradi T, Schaeff K, Garcia-Rivera EM, Itzhak DN, Schmidt RM, Bircham PW, Leiss K, Diaz-Miyar J, Chen VK, Muzzey D, Borner GHH, Schuck S (2018) SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress. Mol Cell, doi: 10.1016/j.molcel.2018.04.027

Klingenberg M, Groß M, Goyal A, Polycarpou-Schwarz M, Miersch T, Ernst AS, Leupold J, Patil N, Warnken U, Allgayer H, Longerich T, Schirmacher P, Boutros M, Diederichs S (2018) The lncRNA CASC9 and RNA binding protein HNRNPL form a complex and co-regulate genes linked to AKT signaling. Hepatology, doi: 10.1002/hep.30102

Szoradi T, Schaeff K, Garcia-Rivera EM, Itzhak DN, Schmidt RM, Bircham PW, Leiss K, Diaz-Miyar J, Chen VK, Muzzey D, Borner GHH, Schuck S (2018) SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress. Mol Cell, doi: 10.1016/j.molcel.2018.04.027

Göttlich C, Kunz M, Zapp C, Nietzer SL, Walles H, Dandekar T, Dandekar G (2018) A combined tissue engineered / in silico signature tool for patient stratification in lung cancer. Mol Oncol, doi: 10.1002/1878-0261.12323

Sánchez MF, Murad F, Gülcüler Balta GS, Martin-Villalba A, García-Sáez AJ, Carrer DC (2018) Early activation of CD95 is limited and localized to the cytotoxic synapse. FEBS J, doi: 10.1111/febs.14518

Herrmann AK, Grimm D (2018) High-Throughput Dissection of AAV-Host Interactions: The Fast and the Curious. J Mol Biol, doi: 10.1016/j.jmb.2018.05.022

Prinz H, Sattler JM, Roth A, Ripp J, Adams JH, Frischknecht F (2018) Immunization efficacy of cryopreserved genetically attenuated Plasmodium berghei sporozoites. Parasitol Res, doi: 10.1007/s00436-018-5937-0

de Sena Cortabitarte A, Berkel S, Cristian FB, Fischer C, Rappold GA (2018) A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders J Neurodev Disord, 10, 1, 15

Boehler S, Lörracher AK, Schubert J, Braunbeck T (2018) Comparative live-imaging of in vivo EROD (ethoxyresorufin-O-deethylase) induction in zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) embryos after exposure to PAHs and river sediment extracts. Sci Total Environ, 621, 827-838

Schopp IM, Béthune J (2018) Split-BioID - Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment. J Vis Exp, doi: 10.3791/57479

Paredes I, Himmels P, Ruiz de Almodóvar C (2018) Neurovascular Communication during CNS Development. Dev Cell, 45, 1, 10-32

Litke C, Bading H, Mauceri D (2018) Histone deacetylase 4 shapes neuronal morphology via a mechanism involving regulation of expression of Vascular Endothelial Growth Factor D. J Biol Chem, doi: 10.1074/jbc.RA117.001613

Montalbano A, Juergensen L, Fukami M, Thiel CT, Hauer NH, Roeth R, Weiss B, Naiki Y, Ogata T, Hassel D, Rappold GA (2018) Functional missense and splicing variants in the retinoic acid catabolizing enzyme CYP26C1 in idiopathic short stature. Eur J Hum Genet, doi: 10.1038/s41431-018-0148-9

Kuk H, Arnold C, Wagner AH, Hecker M, Sticht C, Korff T (2018) Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice. Front Physiol, 9, 320

Dimou E, Nickel W (2018) Unconventional mechanisms of eukaryotic protein secretion. Curr Biol, 28, 8, R406-R410

Rocker A, Peschke M, Kittilä T, Sakson R, Brieke C, Meinhart A (2018) The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis. Nat Commun, 9, 1, 1686

Venkataramani V, Kardorff M, Herrmannsdörfer F, Wieneke R, Klein A, Tampé R, Heilemann M, Kuner T (2018) Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins. Sci Rep, 8, 1, 5507

Pfarr S, Schaaf L, Reinert JK, Paul E, Herrmannsdörfer F, Roßmanith M, Kuner T, Hansson AC, Spanagel R, Körber C, Sommer WH (2018) Choice for Drug or Natural Reward Engages Largely Overlapping Neuronal Ensembles in the Infralimbic Prefrontal Cortex. J Neurosci, 38, 14, 3507-3519

Lust K, Sinn R, Pérez Saturnino A, Centanin L, Wittbrodt J (2018) De novo neurogenesis by targeted expression of Atoh7 to Müller glia cells. Development, doi: 10.1242/dev.135905

Muthinja JM, Ripp J, Krüger T, Imle A, Haraszti T, Fackler OT, Spatz JP, Engstler M, Frischknecht F (2018) Tailored environments to study motile cells and pathogens. Cell Microbiol, 20, 3

Sachdeva R, Schlotterer A, Schumacher D, Matka C, Mathar I, Dietrich N, Medert R, Kriebs U, Lin J, Nawroth P, Birnbaumer L, Fleming T, Hammes HP, Freichel M (2018) TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation. Mol Metab, 9, 156-167

Chase AJ, Wombacher R, Fackler OT (2018) Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef. J Biol Chem, doi: 10.1074/jbc.RA118.002794

Abu El Maaty MA, Almouhanna F, Wölfl S (2018) Expression of TXNIP in Cancer Cells and Regulation by 1,25(OH)2D3: Is It Really the Vitamin D3 Upregulated Protein? Int J Mol Sci, 19, 3, 796

Poppelreuther M*, Sander S*, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J (*equal contribution) (2018) The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells. Biochim Biophys Acta, doi: 10.1016/j.bbalip.2018.03.003.

Duffey M, Sanchez CP, Lanzer M (2018) Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum. Malar J, 17, 1, 121

Bucher D, Frey F, Sochacki KA, Kummer S, Bergeest JP, Godinez WJ, Kräusslich HG, Rohr K, Taraska JW, Schwarz US, Boulant S (2018) Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis. Nat Commun, 9, 1, 1109

Platten M, Bunse L, Riehl D, Bunse T, Ochs K, Wick W (2018) Vaccine Strategies in Gliomas. Curr Treat Options Neurol, 20, 5, 11

Wirthschaft P, Bode J, Simon AEM, Hoffmann E, van Laack R, Krüwel T, Dietrich F, Bucher D, Hahn A, Sahm F, Breckwoldt MO, Kurz FT, Hielscher T, Fischer B, Dross N, Ruiz de Almodovar C, von Deimling A, Herold-Mende C, Plass C, Boulant S, Wiestler B, R (2018) A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas. Int J Cancer, doi: 10.1002/ijc.31404

Alvisi G, Paolini L, Contarini A, Zambarda C, Di Antonio V, Colosini A, Mercandelli N, Timmoneri M, Palù G, Caimi L, Ricotta D, Radeghieri A (2018) Intersectin goes nuclear: secret life of an endocytic protein. Biochem J, doi: 10.1042/BCJ20170897

Dimitrov B, Himmelreich N, Hipgrave Ederveen AL, Lüchtenborg C, Okun JG, Breuer M, Hutter AM, Carl M, Guglielmi L, Hellwig A, Thiemann KC, Jost M, Peters V, Staufner C, Hoffmann GF, Hackenberg A, Paramasivam N, Wiemann S, Eils R, Schlesner M...Thiel (2018) Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG. Mol Genet Metab, 123, 3, 364-374

Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, S...Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V (2018) Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll Like Receptor 3 in Hepatocytes. Gastroenterology, doi: 10.1053/j.gastro.2018.03.020

Zhang Z, Filzmayer C, Ni Y, Sültmann H, Mutz P, Hiet MS, Vondran FWR, Bartenschlager R, Urban S (2018) Hepatitis D Virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes. J Hepatol, doi: 10.1016/j.jhep.2018.02.021

Heigwer F, Port F, Boutros M (2018) RNA Interference (RNAi) Screening in Drosophila. Genetics, 208, 3, 853-874

Font-Haro A, Janovec V, Hofman T, Machala L, Jilich D, Melkova Z, Weber J, Trejbalova K, Hirsch I (2018) Expression of TIM-3 on Plasmacytoid Dendritic Cells as a Predictive Biomarker of Decline in HIV-1 RNA Level during ART. Viruses, 10, 4, E154

Naharros IO, Cristian FB, Zang J, Gesemann M, Ingham PW, Neuhauss SCF, Bachmann-Gagescu R (2018) The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance. Sci Rep, 8, 1, 2211

Zhang W, Neuner A, Rüthnick D, Sachsenheimer T, Lüchtenborg C, Brügger B, Schiebel E (2018) Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis. J Cell Biol, doi: 10.1083/jcb.201706024

Takemoto K, Ebine K, Askani JA, Krüger F, Gonzalez ZA,Ito E, Goh T, Schumacher K, Nakano A, Ueda T (2018) Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis Proc Natl Acad Sci U S A, https://doi.org/10.1073/pnas.1717839115

Voloshanenko O, Schwartz U, Kranz D, Rauscher B, Linnebacher M, Augustin I, Boutros M (2018) β-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells. Sci Rep, 8, 1, 3178

Vlijm R, Li X, Panic M, Rüthnick D, Hata S, Herrmannsdörfer F, Kuner T, Heilemann M, Engelhardt J, Hell SW, Schiebel E (2018) STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles. Proc Natl Acad Sci U S A, https://doi.org/10.1073/pnas.1716840115

Mulindwa J, Leiss K, Ibberson D, Kamanyi Marucha K, Helbig C, Melo do Nascimento L, Silvester E, Matthews K, Matovu E, Enyaru J, Clayton C (2018) Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods. PLoS Negl Trop Dis, 12, 2, e0006280

Garcia Del Arco A, Edgar BA, Erhardt S (2018) In Vivo Analysis of Centromeric Proteins Reveals a Stem Cell-Specific Asymmetry and an Essential Role in Differentiated, Non-proliferating Cells. Cell Rep, 22, 8, 1982-1993

Li C, Cesbron F, Oehler M, Brunner M, Höfer T (2018) Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation. Cell Syst, doi: 10.1016/j.cels.2018.01.012

Gröbner SN...Huebschmann D...Pfister SM (2018) The landscape of genomic alterations across childhood cancers. Nature, doi: 10.1038/nature25480

Brackmann K, Qi J, Gebert M, Jouannet V, Schlamp T, Grünwald K, Wallner ES, Novikova DD, Levitsky VG, Agustí J, Sanchez P, Lohmann JU, Greb T (2018) Spatial specificity of auxin responses coordinates wood formation. Nat Commun, 9, 1, 875

Gülmez Karaca K, Brito DVC, Zeuch B, Oliveira AMM (2018) Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation. Neurobiol Learn Mem, 149, 84-97

Wiedenmann T, Dietrich N, Fleming T, Altamura S, Deelman LE, Henning RH, Muckenthaler MU, Nawroth PP, Hammes HP, Wagner AH, Hecker M (2018) Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice. J Diabetes Complications, 32, 2, 130

Rauscher B, Heigwer F, Henkel L, Hielscher T, Voloshanenko O, Boutros M (2018) Toward an integrated map of genetic interactions in cancer cells. Mol Syst Biol, 14, 2, e7656

Janovec V, Aouar B, Font-Haro A, Hofman T, Trejbalova K, Weber J, Chaperot L, Plumas J, Olive D, Dubreuil P, Nunès JA, Stranska R, Hirsch I (2018) The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells. Front Immunol, 9, 364

Mutlu A, Trauth S, Ziesack M, Nagler K, Bergeest JP, Rohr K, Becker N, Höfer T, Bischofs IB (2018) Phenotypic memory in Bacillus subtilislinksdormancy entry and exit by a spore quantity-quality tradeoff. Nat Commun, 9, 1, 69

Coquelle N, Sliwa M, Woodhouse J, Schirò G, Adam V, Aquila A, Barends TRM, Boutet S, Byrdin M, Carbajo S, De la Mora E, Doak RB, Feliks M, Fieschi F, Foucar L, Guillon V, Hilpert M, Hunter MS, Jakobs S, Koglin JE, Kovácsová G,...Schlichting I, Weik M (2018) Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography. Nat Chem, 10, 1, 31-37

Arnold C, Demirel E, Feldner A, Genové G, Zhang H, Sticht C, Wieland T, Hecker M, Heximer S, Korff T (2018) Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5. FASEB J, doi: 10.1096/fj.201700384RR

Theobald J, Ghanem A, Wallisch P, Banaeiyan AA, Andrade-Navarro MA, Taškova K, Haltmeier M, Kurtz A, Becker H, Reuter S, Mrowka R, Cheng X, Wölfl S (2018) Liver-Kidney-on-Chip To Study Toxicity of Drug Metabolites. ACS Biomater Sci Eng, 4, 1, 78–89

Grousl T, Ungelenk S, Miller S, Ho CT, Khokhrina M, Mayer MP, Bukau B, Mogk A (2018) A prion-like domain in Hsp42 drives chaperone-facilitated aggregation of misfolded proteins. J Cell Biol, doi: 10.1083/jcb.201708116

Schmelas C, Grimm D (2018) Split Cas9, not hairs - advancing the therapeutic index of CRISPR technology. Biotechnol J, doi: 10.1002/biot.201700432

Ebersoll S, Musunda B, Schmenger T, Dirdjaja N, Bonilla M, Manta B, Ulrich K, Comini MA, Krauth-Siegel RL (2018) A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes. Redox Biol, 15, 532-547

Haas J,Mester S,Lai A,Frese KS,Sedaghat-Hamedani F,Kayvanpour E,Rausch T,Nietsch R,Boeckel JN,Völkers M,Dietrich C,Pils D,Amr A,Bordalo DM,Weis T,Mereles D,Buss S,Riechert E,Wirsz E, Wuerstle M,Korbel JO,Keller A,Katus HA,Posch AE,Meder B (2018) Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy EMBO Molecular Medicine, Volume 10, No.1 107-120