Ruprecht-Karls-Universität Heidelberg
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Adam, Gordian

Gordian Adam

Date of graduation:
Oct 2012
PhD supervisor:
Prof. Dr. Hellmut G. Augustin
Position after graduation:
Postdoc, Bayer Heathcare, Berlin

Field of interest:

Cancer research is the area of biology that I’m most interested in, as cancer is the second most common cause of death in the western world. I therefore put my main emphasis on Molecular Medicine and Pharmaceutical Chemistry during my studies and chose to perform my diploma thesis research in the tumor progression research group of the University Women’s Hospital in Tübingen. For my PhD, I chose the Joint Research Group of Vascular Biology with laboratories at the German Cancer Research Center in Heidelberg and the CBTM in Mannheim, because during my work on cancer I realized that different types of cancer have different causes, but nearly all of them require neoangiogenesis for nutrition and removal of detritus. I hope to gain knowledge of the molecules and pathways involved in vascular development on cellular level, so I will be able to help to find a way to interfere with these to starve out or suffocate tumors. Angiogenesis research is a fascinating field, because the mechanisms that control the growth of blood vessels can be used to treat a variety of diseases. Once the signaling pathways are understood it will be possible to design drugs that block vascularisation, which is favourable for cancer treatment, as well as other drugs that enhance angiogenesis, which would be valuable for treatment of diseases like ischemia or stroke.

Curriculum Vitae

2008 
-
2012 
University education
PhD student
Prof. Dr. Hellmut G. Augustin
German Cancer Research Center (DKFZ)

2008 
-
 
Awards
IMS/Bayer Schering Pharma Hermann Schneider prize for the best communication on menopause and breast health

2007 
-
2008 
University education
University Women’s Hospital Tübingen, Germany

2006 
-
 
University education
Ludwig-Maximilians-University Munich, Germany

2002 
-
2008 
University education
Eberhard-Karls-University Tübingen, Germany

Publications

Synaptojanin-2 Binding Protein Stabilizes the Notch Ligands DLL1 and DLL4 and Inhibits Sprouting Angiogenesis. (2013) Adam G, Berger C, Feldner A, Yang WJ, Wüstehube-Lausch J, Herberich SE, Pinder M, Gesierich S, Hammes HP, Augustin HG, Fischer A Circ Res, 113, 11, 1206-18

No Evidence for a Functional Role of Bi-Directional Notch Signaling during Angiogenesis. (2012) Liebler SS, Feldner A, Adam G, Korff T, Augustin HG, Fischer A. PLoS One, 7, 12, e53074

Integrin Cytoplasmic Domain-Associated Protein-1 Attenuates Sprouting Angiogenesis. (2010) Brütsch R, Liebler SS, Wüstehube J, Bartol A, Herberich SE, Adam G, Telzerow A, Augustin HG, Fischer A Circulation Research, 107, 5, 592-601

Membrane-initiated effects of progesterone on proliferation and activation of VEGF in breast cancer cells. (2009) Neubauer H*, Adam G*, Seeger H, Mueck AO, Solomayer E, Wallwiener D, Cahill MA, Fehm T Climacteric, 212, 3, 230-239